Ypsomed has an impressive track record documenting the long experience in development, filing support and manufacturing of self-injection devices. Amongst the publicly known customers of Ypsomed are Pfizer, Sanofi, Roche/Genentech, Eli Lilly, Merck, GSK, AstraZeneca and many more. Below are just a few examples of Ypsomed’s self-injection milestones:
YpsoDot – Product innovation reveal
In October, Ypsomed revealed YpsoDot, the pull & push self-injection pen for fixed doses up to 1 mL. Made from a single eco-material and following ecodesign principles from day one, the pen aims to reduce the environmental footprint.
YpsoLoop – Product launch 2025
On 21st October 2025 during PDA, Ypsomed launched YpsoLoop, the first autoinjector designed for circularity - enabling material recovery through automated disassembly and efficient recycling while offering injection guidance through ClickGuide® technology and integrating into existing pharma supply chains.
CliniPilot – Product launch, 2025
CliniPilot brings connectivity to the YpsoMate and YpsoMate 2.25 mL platform, supporting decentralized study designs, EDC integration and real-time data capture.
YpsoFlow – Product launch, 2025
Ypsomed introduces YpsoFlow, a spring-driven, pre-filled pen launched at CPHI China, designed for effortless injections and sustainability — advancing the company’s eco-design leadership in pen platforms.
UnoPen enters NetZero Program, 2025
Sustainability meets versatility: UnoPen becomes the latest Ypsomed platform available as a low-carbon device.
YpsoDose wins gold at CPHI China for drug delivery innovation, 2025
Ypsomed’s large-volume patch injector platform YpsoDose receives the Gold Award for Drug Delivery Innovation at CPHI China — recognizing its breakthrough role in redefining self-injection.
YpsoMate platform with 8 mm needle option, 2024
New needle configuration and strategic partnership with BD expand YpsoMate’s capabilities for high-viscosity biologics.
YpsoMate 2.25 joins NetZero Program, 2024
Expanding sustainability across platform sizes with a low-carbon solution for high-volume biologics.
Reusable autoinjector unveiled at PDA conference, 2023
Ypsomed showcases its upcoming reusable autoinjector concept at a leading industry forum.
Partnership with S3 Connected Health, 2023
Expanding digital health capabilities through therapy-specific patient solutions.
Partnership with Sidekick Health, 2022
Digital therapeutics partnership to enhance patient support during self-injection.
YpsoMate 5.5 – Product launch, 2022
Ypsomed redefines subcutaneous drug delivery with YpsoMate 5.5, allowing injection volumes up to 5.5 mL, following eco-design guidelines and offering continuous clicking.
Red Dot Award for SmartPilot for UnoPen, 2021
Award-winning connectivity: SmartPilot for UnoPen recognized for design excellence.
YpsoMate On, 2021
Introduction the world’s first autoinjector for prefilled syringes with integrated connectivity.
YpsoMate Zero, 2020
Introduction of YpsoMate Zero the world's first zero carbon emission prefilled autoinjector.
SmartPilot for UnoPen, 2020
Introduction of SmartPilot for UnoPen transforming the dial-and-dose UnoPen into a fully connected system.
FixPen, 2019
First FixPen approval and launch for Teriparatide for treating osteoporosis.
YpsoMate 2.25 for Teva, 2019
Launch of Teva's Ajovy: The world's first approval and launch of a 2.25mL PFS based autoinjector.
YpsoMate, 2019
Launch of 5 additional YpsoMate 1mL autoinjectors in key markets such as US, EU and JP including Teva's Copaxone and Asahi Kasei's Teribone.
YpsoDose, 2019
Introduction of the YpsoDose pre-filled and pre-assembled large volume patch injector.
SmartServices, 2019
Ypsomed teams up with Philips for the development of its new SmartServices to simplify medication adherence monitoring.
YpsoMate for Terumo, 2018
First YpsoMate 1mL approval and launch for Mylan/FKB's Hulio (adalimumab) for the treatment of chronic autoimmune diseases.
SmartPilot for YpsoMate, 2017
Introduction of SmartPilot for YpsoMate transforming the proven YpsoMate autoinjector into a smart product system.
YpsoMate 2.25 Pro, 2016
Introduction of an autoinjector suitable for 2.25ml syringes and viscous injection volumes up to 2.25ml. A high power constant force spring is capable to inject highly viscous formulations.
YpsoMate 2.25, 2015
Introduction of an autoinjector suitable for the 2.25ml syringe and injection volumes up to 2.25ml.
LyoTwist Trio for AstraZeneca, 2014
Introduction of a customized version of LyoTwist Trio for AstraZeneca’s Bydureon-Pen.
LyoTwist Trio for GSK, 2014
Introduction of a customized version of LyoTwist Trio for GSK’s Tanzeum™/Eperzan®.
UnoPen, 2014
Introduction and first launch of the prefilled UnoPen for insulin and other multidose therapies providing a familiar handling experience and high level of patient acceptance.
YpsoPen for Dongbao, 2013
Launch of YpsoPen, the intuitive dial & dose reusable pen, for Dongbao's Sulin insulin
YpsoMate, 2011
Introduction of a new 2-step “buttonless” autoinjector that sets new standards for simplicity and patient feedback. YpsoMate is currently being used by a number of customers for clinical trials in a range of therapeutic indications.
ServoPen for Dongbao, 2010
The first reusable automatic insulin pen that won the red dot design award, launched first as Gansulin Pen in China and in customized versions in other markets.
OptiSet for Sanofi, 1999
With this new generation of a disposable insulin pen, Ypsomed set a benchmark in the industry.
KabiPen for Kabi Pharmacia (Pfizer), 1989
The world’s first pen for human growth hormone and for dual-chamber cartridges. With this pen Ypsomed built the foundation for pens compatible with dual-chamber cartridges.
OptiPen for Hoechst (Sanofi), 1985
As one of the world’s first insulin pens this pen is considered to be one of the forerunners of all following generations of insulin pens.