Ypsomed has an impressive track record documenting the long experience in development, filing support and manufacturing of self-injection devices. Amongst the publicly known customers of Ypsomed are Pfizer, Sanofi, Roche/Genentech, Eli Lilly, Merck, GSK, AstraZeneca and many more. Below are just a few examples of Ypsomed’s self-injection milestones:

YpsoDot – Product innovation reveal

In October, Ypsomed revealed YpsoDot, the pull & push self-injection pen for fixed doses up to 1 mL. Made from a single eco-material and following ecodesign principles from day one, the pen aims to reduce the environmental footprint.

YpsoLoop – Product launch 2025

On 21st October 2025 during PDA, Ypsomed launched YpsoLoop, the first autoinjector designed for circularity - enabling material recovery through automated disassembly and efficient recycling while offering injection guidance through ClickGuide® technology and integrating into existing pharma supply chains.

CliniPilot – Product launch, 2025

CliniPilot brings connectivity to the YpsoMate and YpsoMate 2.25 mL platform, supporting decentralized study designs, EDC integration and real-time data capture.

YpsoFlow – Product launch, 2025

Ypsomed introduces YpsoFlow, a spring-driven, pre-filled pen launched at CPHI China, designed for effortless injections and sustainability — advancing the company’s eco-design leadership in pen platforms.

UnoPen enters NetZero Program, 2025

Sustainability meets versatility: UnoPen becomes the latest Ypsomed platform available as a low-carbon device.

YpsoDose wins gold at CPHI China for drug delivery innovation, 2025

Ypsomed’s large-volume patch injector platform YpsoDose receives the Gold Award for Drug Delivery Innovation at CPHI China — recognizing its breakthrough role in redefining self-injection.

YpsoMate platform with 8 mm needle option, 2024

New needle configuration and strategic partnership with BD expand YpsoMate’s capabilities for high-viscosity biologics.

YpsoMate 2.25 joins NetZero Program, 2024

Expanding sustainability across platform sizes with a low-carbon solution for high-volume biologics.

Reusable autoinjector unveiled at PDA conference, 2023

Ypsomed showcases its upcoming reusable autoinjector concept at a leading industry forum.

Partnership with S3 Connected Health, 2023

s3 connected health logo

Expanding digital health capabilities through therapy-specific patient solutions.

Partnership with Sidekick Health, 2022

Digital therapeutics partnership to enhance patient support during self-injection.

YpsoMate 5.5 – Product launch, 2022

YpsoMate 5.5 autoinjector with ergonomic design. Features gripping area for stable handling and clear injection process feedback.

Ypsomed redefines subcutaneous drug delivery with YpsoMate 5.5, allowing injection volumes up to 5.5 mL, following eco-design guidelines and offering continuous clicking.

Red Dot Award for SmartPilot for UnoPen, 2021

Award-winning connectivity: SmartPilot for UnoPen recognized for design excellence.

YpsoMate On, 2021

The YpsoMate On is a white autoinjector with a blue label towards the back. The label reads "YpsoMate" and has a button on the side labeled "On," indicating it is powered on. This is the first autoinjector for prefilled syringes with integrated connectivi

Introduction the world’s first autoinjector for prefilled syringes with integrated connectivity.

YpsoMate Zero, 2020

Image features the YpsoMate Zero autoinjector. It has white, silver, and gold-colored housing with the Ypsomed logo and "Zero" written on the side.

Introduction of YpsoMate Zero the world's first zero carbon emission prefilled autoinjector.

SmartPilot for UnoPen, 2020

SmartPilot for UnoPen: A connected insulin pen add-on. Enhances traditional pen with digital features.

Introduction of SmartPilot for UnoPen transforming the dial-and-dose UnoPen into a fully connected system.

FixPen, 2019

A single, white FixPen, used to inject Teriparatide for the treatment of Osteoporosis, lies horizontally with a protective end cover. The pen has text on the side that reads "FixPen".

First FixPen approval and launch for Teriparatide for treating osteoporosis.

YpsoMate 2.25 for Teva, 2019

Ajovy 225mg autoinjector, a prefilled syringe for migraine treatment.

Launch of Teva's Ajovy: The world's first approval and launch of a 2.25mL PFS based autoinjector.

YpsoMate, 2019

YpsoMate autoinjector for medications like Copaxone and Teribone.

Launch of 5 additional YpsoMate 1mL autoinjectors in key markets such as US, EU and JP including Teva's Copaxone and Asahi Kasei's Teribone.

YpsoDose, 2019

YpsoDose patch injector, pre-filled and pre-assembled for large volume subcutaneous drug delivery.

Introduction of the YpsoDose pre-filled and pre-assembled large volume patch injector.

SmartServices, 2019

YpsoMate for Terumo, 2018

Hulio pre-filled pen (adalimumab), 40mg dose. Treatment for autoimmune diseases. Mylan/FKB's first YpsoMate approval.

First YpsoMate 1mL approval and launch for Mylan/FKB's Hulio (adalimumab) for the treatment of chronic autoimmune diseases.

SmartPilot for YpsoMate, 2017

SmartPilot for YpsoMate, an autoinjector pen with a digital interface and green end cap, designed for smart drug delivery.

Introduction of SmartPilot for YpsoMate transforming the proven YpsoMate autoinjector into a smart product system.

YpsoMate 2.25 Pro, 2016

YpsoMate 2.25 Pro autoinjector, designed for viscous injection volumes up to 2.25ml. The device has a blue cap and a clear window to view the syringe. It uses a constant force spring for injecting high-viscosity drugs.

Introduction of an autoinjector suitable for 2.25ml syringes and viscous injection volumes up to 2.25ml. A high power constant force spring is capable to inject highly viscous formulations.

YpsoMate 2.25, 2015

A prefilled YpsoMate autoinjector. It features a clear window to show the medication, and is designed for subcutaneous delivery of up to 2.25ml.

Introduction of an autoinjector suitable for the 2.25ml syringe and injection volumes up to 2.25ml.

LyoTwist Trio for AstraZeneca, 2014

Bydureon Pen injector with custom green and orange twisting design. AstraZeneca product for weekly injection.

Introduction of a customized version of LyoTwist Trio for AstraZeneca’s Bydureon-Pen.

LyoTwist Trio for GSK, 2014

Tanzeum™/Eperzan® LyoTwist Trio device showing a 30 mg dose.

Introduction of a customized version of LyoTwist Trio for GSK’s Tanzeum™/Eperzan®.

UnoPen, 2014

Close-up of a UnoPen prefilled injector pen for insulin and multidose therapies, designed for ease of use and patient acceptance. The pen is white with black text and a dose display window.

Introduction and first launch of the prefilled UnoPen for insulin and other multidose therapies providing a familiar handling experience and high level of patient acceptance.

YpsoPen for Dongbao, 2013

Sulin Pen, a green insulin pen with dial for dosage. Part of the YpsoPen launch with Dongbao.

Launch of YpsoPen, the intuitive dial & dose reusable pen, for Dongbao's Sulin insulin

YpsoMate, 2011

YpsoMate autoinjector, a buttonless injection device for clinical trials.

Introduction of a new 2-step “buttonless” autoinjector that sets new standards for simplicity and patient feedback. YpsoMate is currently being used by a number of customers for clinical trials in a range of therapeutic indications.

ServoPen for Dongbao, 2010

Gansulin Pen, a reusable green insulin injection pen, with a black dosage selector.

The first reusable automatic insulin pen that won the red dot design award, launched first as Gansulin Pen in China and in customized versions in other markets.

OptiSet for Sanofi, 1999

Disposable insulin pen for self-injection with dose indicator. White plastic design, clear reservoir showing insulin level.

With this new generation of a disposable insulin pen, Ypsomed set a benchmark in the industry.

KabiPen for Kabi Pharmacia (Pfizer), 1989

KabiPen: A pen-injector for human growth hormone, suitable for dual-chamber cartridges.

The world’s first pen for human growth hormone and for dual-chamber cartridges. With this pen Ypsomed built the foundation for pens compatible with dual-chamber cartridges.

OptiPen for Hoechst (Sanofi), 1985

OptiPen insulin injector, a forerunner in injector pen technologies.

As one of the world’s first insulin pens this pen is considered to be one of the forerunners of all following generations of insulin pens.